منابع مشابه
Nonsteroid anti-inflammatory drug-induced gastroduodenal injury.
PURPOSE OF REVIEW This article reviews selected publications related to nonsteroid anti-inflammatory drug (NSAID)-induced gastroduodenal toxicity in recent years. RECENT FINDINGS This article provides a comprehensive review of the latest evidence on the epidemiology of NSAID-induced gastroduodenal injury, recommendations on optimal gastroprotective regimens among patients in need of NSAID, ri...
متن کامل[Cycloxygenase-2 inhibitors nonsteroid anti-inflammatory drugs: current issues.].
BACKGROUND AND OBJECTIVES Due to the high incidence of NSAID-related side-effects, the discovery of two cycloxygenase isoforms, classified as: COX-1 or constitutive and COX-2 or inductive, has formulated the paradigm that NSAIDs anti-inflammatory properties would be mediated by COX-2 inhibition, and side-effects, by COX-1 blockade. However, COX-2 has been constitutively detected in normal tissu...
متن کاملNew anti-inflammatory agents.
The pyrrole derivatives la, b and 2a, b were used as precursors for the preparation of N-substituted pyrrole derivatives 3a, b-9a, b and pyrrolo[2,3-d]pyrimidines 13-16. Also, all the newly prepared products were tested for anti-inflammatory activity as analogues to fenamates, and some of them revealed moderate anti-inflammatory activity compared to the standard drug indomethacin.
متن کاملAnti-inflammatory and Analgesic Agents
Inflammatory diseases including arthritis and rheumatism are major group of prevalent diseases. Most of the available non-steroidal anti-inflammatory drugs are effective in inflammatory conditions of the joints, but are devoid of gastro protective property. Many substances, interfering with the inflammatory response have been isolated from Indian medicinal plants (IMP). The review analyses form...
متن کاملDendrimers as anti-inflammatory agents
Pramod Avti is a Postdoctoral Fellow at Montreal Heart Institute, Montreal, Q u e b e c , C a n a d a w o r k i n g o n a collaborative project with Department of Chemistry, McGill University and Ecole Polytechnique, Montreal Canada. His current scientific interests include multifunctional nanomaterials synthesis, and their biomedical applications. In particular, his research is aimed at synthe...
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ژورنال
عنوان ژورنال: Annual Review of Pharmacology
سال: 1966
ISSN: 0066-4251
DOI: 10.1146/annurev.pa.06.040166.001105